How do you get functional asplenia?

How do you get functional asplenia?

A small spleen with absent parenchymal vascularization on color Doppler ultrasonography has been associated with functional asplenia, but this should be confirmed with further imaging before declaring a patient functionally asplenic. The absence of the spleen is best confirmed with a technetium-99m radionuclide scan.

What is functional asplenia?

Anatomic asplenia is most often due to surgical splenectomy, performed for trauma or therapeutically (eg, for hemolytic anemias or immune thrombocytopenias) [1]. Functional asplenia refers to complete loss of function caused by medical conditions and occurs most frequently with sickle cell anemia [2].

What causes functional asplenia in sickle cell?

Functional asplenia occurs when splenic tissue is present but does not work well (e.g. sickle-cell disease, polysplenia) -such patients are managed as if asplenic-, while in anatomic asplenia, the spleen itself is absent.

Can splenic sequestration cause death?

During severe sequestration crisis, the blood-filled spleen may enlarge to the point of filling the entire abdomen. The child’s hemoglobin may drop rapidly (to as low as 1-3g/dl) resulting in hypovolemic shock (low level of blood in the circulation results in lack of blood to all organs) and death within hours.

Is asplenia a chronic health condition?

Vaccines are especially critical for people with chronic health conditions such as asplenia.

What is asplenia syndrome?

Asplenia syndrome is a syndrome of right isomerism or attempted bilateral right sidedness. It includes congenital asplenia in association with complex congenital cyanotic heart disease and situs anomalies of the other thoracoabdominal organs.

How does asplenia affect immune system?

If the spleen does not work properly, it may start to remove healthy blood cells. This can lead to: anaemia, from a reduced number of red blood cells. an increased risk of infection, from a reduced number of white blood cells.

What triggers splenic sequestration?

Acute splenic sequestration happens when sickled red blood cells get trapped in the spleen, causing the spleen to enlarge. Sickle cell disease affects the red blood cells causing them to sickle or become banana-shaped. The main purpose of red blood cells (RBCs) is to deliver oxygen to the body.

What are the symptoms of splenic sequestration?

What are the symptoms of splenic sequestration?

  • Irritability.
  • Pain on the left side of the abdomen.
  • Weakness.
  • Fast heart rate.
  • Big spleen.
  • Unusual Sleepiness.
  • Looks pale.

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