How does the rubella virus infect cells?
How does the rubella virus infect cells?
Pathogenesis. The disease is transmitted via direct or droplet contact with respiratory secretions. Rubella virus multiplies in cells of the respiratory system; this is followed by viremic spread to target organs. Congenital infection is transmitted transplacentally.
What is rubella antigen?
A rubella blood test detects antibodies that are made by the immune system to help kill the rubella virus. These antibodies remain in the bloodstream for years. The presence of certain antibodies means a recent infection, a past infection, or that you have been vaccinated against the disease.
What is a receptor in a virus?
A virus receptor can be defined as a host cell surface component recognized by the virus as a gateway to entry into the cell. From: Brain Lipids in Synaptic Function and Neurological Disease, 2015.
Is rubella RNA positive or negative?
Rubella virus is an enveloped, positive-stranded RNA virus classified as a Rubivirus in the Matonaviridae family.
What is the pathophysiology of rubella virus?
The pathophysiology of rubella is not completely understood. Viral replication in the respiratory epithelium occurs following transmission of the virus via contact with droplet secretions from an infected person. Viremia subsequently ensues, with the onset of the rubella rash occurring at the peak of viremia.
What is the portal of entry for rubella?
The usual portal of entry of rubella virus is the respiratory epithelium of the nasopharynx. The virus is transmitted via the aerosolized particles from the respiratory tract secretions of infected individuals.
Do all viruses have receptors?
All viruses need to bind to specific receptor molecules on the surface of target cells to initiate infection. Virus–receptor binding is highly specific, and this specificity determines both the species and the cell type that can be infected by a given virus.
Do virus have receptors?
Viruses have evolved to recognize cellular receptors and enter cells despite the presence of the host immune system.
What cell type does rubella infect?
Replication
| Genus | Host details | Assembly site |
|---|---|---|
| Rubivirus | Humans | Cytoplasm |
What are the virulence factors of rubella virus?
Capsid protein is a virulence factor of the rubella virus because it can assist virus replicate in the host cells and help the virus escape from immune response of the host.