How many people a year are diagnosed with APL?

How many people a year are diagnosed with APL?

In the United States, acute promyelocytic leukemia (APL) accounts for 5-15% of all adult leukemias. Approximately 30,800 cases of acute leukemia are diagnosed yearly in the US, and about 1000 of those are APL.

How common is leukemia worldwide?

Global level There were approximately 2.43 million (95% UI 2.19 million to 2.59 million) prevalent cases of leukemia, with an age-standardized prevalence rate (ASPR) of 32.26 (95% UI 29.02 to 34.61) per 100,000 population in 2017.

What is the survival rate of APL?

APL is now considered a highly curable disease, with 2-year event-free survival rates of 75–84%. Early mortality is common in APL and is frequently related to hemorrhagic complications. Prior to ATRA therapy, early death (ED) related to hemorrhage occurred in up to 26% of cases.

Is acute promyelocytic leukemia rare?

Acute promyelocytic leukaemia (APML) is a rare sub-type of acute myeloid leukaemia (AML) and is sometimes referred to as AML M31. APML accounts for only 10% of all AML diagnoses. In APML, immature abnormal neutrophils (a type of white blood cell) known as promyelocytes accumulate in the bone marrow.

Is APL a rare disease?

APL is a rare sub-type of acute myeloid leukaemia (AML). When you have APL, the bone marrow is not able to make enough normal blood cells. APL is treated in a very different way from other forms of AML, if a patient with APL is given standard treatment, there is a risk of serious problems with their clotting system.

What country is leukemia most common in?

Five countries with the highest number of Leukemia in females were China with 27384 cases, the United States with 17225 cases, India with 12913 cases, Russia with 5903 cases, and Germany with 4767 cases. The ASIR of leukemia per 100,000 people in the world was 4.7 (in men was 5.6 and in women was 3.9).

What race is most affected by leukemia?

Leukemia is more common in men than in women, and more common in Caucasians than in African-Americans. Although leukemia is rare in children, of the children or teens who develop any type of cancer, 30% will develop some form of leukemia.

How curable is APL leukemia?

Because of advances in diagnostic techniques and modern treatments, APL is today considered to be the most curable subtype of acute myeloid leukemia in adults, with complete remission rates of 90 percent and cure rates of approximately 80 percent and even higher among low-risk patients.

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