Is there a generic for GRANIX?
Is there a generic for GRANIX?
Granulocyte – colony stimulating factor (G-CSF) is another name for filgrastim. In some cases, health care professionals may use the trade name Neupogen, Granix or Zarxio when referring to the generic drug name filgrastim.
Can GRANIX be self administered?
GRANIX may be administered by either a healthcare professional or by a patient or caregiver. Before a decision is made to allow GRANIX to be administered by a patient or caregiver, ensure that the patient is an appropriate candidate for self-administration or administration by a caregiver.
How do you administer GRANIX?
The recommended dose of GRANIX is 5 mcg/kg per day administered as a subcutaneous injection. Administer the first dose of GRANIX no earlier than 24 hours following myelosuppressive chemotherapy. Do not administer GRANIX within 24 hours prior to chemotherapy.
Does GRANIX have latex?
GRANIX and all its components are not made with natural rubber latex. Recommended sites for subcutaneous GRANIX injections include the abdomen (except for the two-inch area around the navel), the front of the middle thighs, the upper outer areas of the buttocks, or the upper back portion of the upper arms.
What is the cost of Granix?
The cost for Granix subcutaneous solution (300 mcg/0.5 mL) is around $273 for a supply of 0.5 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Is Granix and Neupogen the same?
Granix is not technically considered a biosimilar to Neupogen because it was filed as a Biologics License Application since a biosimilars approval pathway had not been established at the time of FDA submission.
How fast does GRANIX work?
In cancer patients, the time to achieve a maximum absolute neutrophil count (ANCmax) was 3 to 5 days following administration of Granix, returning to baseline by 21 days after chemotherapy. Median Tmax of Granix is 4 to 6 hours and median half-life of Granix is 3.2 to 3.8 hours.
What are the side effects of GRANIX?
Common side effects of Granix include: bone pain. muscle pain. headache….Seek medical attention if you have signs of an allergic reaction after taking Granix, such as:
- rash.
- shortness of breath.
- wheezing.
- dizziness.
- swelling of the face.
- fast heart rate.
- sweating.
What is GRANIX used for?
Granix (tbo-filgrastim) is an injectable medication used to treat low white blood cells caused by anticancer medications. It’s very similar to the medication Neupogen (filgrastim).
Why is GRANIX given?
GRANIX is indicated to reduce the duration of severe neutropenia in adult and pediatric patients 1 month and older with non-myeloid malignancies receiving myelosuppressive anticancer drugs associated with a clinically significant incidence of febrile neutropenia.
What is the cost of GRANIX?
How is GRANIX made?
GRANIX (tbo-filgrastim) is a non-glycosylated recombinant methionyl human granulocyte colony-stimulating growth factor (r-metHuG-CSF) manufactured by recombinant DNA technology using the bacterium strain E coli K802. It has a molecular weight of approximately 18.8 kDa and is composed of 175 amino acids.