What are the diagnosis of polymyositis?

What are the diagnosis of polymyositis?

As with other muscle diseases, a doctor diagnoses polymyositis (PM) by considering an individual’s history, family medical history and the results of a careful physical examination. This may be followed by some lab tests, perhaps of the electrical activity inside the muscles and usually a muscle biopsy.

How do you explain polymyositis?

Polymyositis is a disease that causes muscles to become irritated and inflamed. The muscles eventually start to break down and become weak. The condition can affect muscles all over the body. This can make even simple movements difficult.

When should you suspect polymyositis?

When to suspect the diagnosis — The diagnosis of dermatomyositis (DM) or polymyositis (PM) should be suspected in patients who present with proximal muscle weakness. The suspicion for DM in particular should be further increased if the patient has a cutaneous eruption suggestive of DM.

How quickly does polymyositis progress?

Polymyositis develops gradually over weeks or months. By the time the person experiences symptoms, they have already lost around half of their muscle fibres to the disease. The head, hands and feet are usually untouched by the disease.

What kind of doctor treats polymyositis?

Patients with dermatomyositis, polymyositis, or necrotizing myopathy are usually treated by rheumatologists. Those with dermatomyositis may also work with a dermatologist. Those with IBM are often treated by neurologists.

How is polymyositis treated?

Polymyositis is treated with high doses of corticosteroids as a first course of treatment. Corticosteroids are given because they can effectively decrease the inflammation in the muscles. Corticosteroids do not always adequately improve polymyositis. In these patients immunosuppressive medications are considered.

What is the life expectancy of polymyositis?

What is the prognosis for patients diagnosed with polymyositis? The 5-year survival rate for adults with polymyositis, according to Merck Manual, is 75 to 80%. Death may result from consequences of severe and progressive muscle weakness. People who have cardiac or pulmonary involvement seem to have a worse prognosis.

What are the prognostic factors for polymyositis?

PROGNOSTIC FACTORS IN POLYMYOSITIS 25 1 The levels of AST, CPK, ALD, and LDH correlated significantly (P < 0.005) with one another, although product-moment correlations were generally low (0.290-0.495). Rheumatoid factor was found in the sera of 6 patients with PM/DM-0s and in 1 patient with PM. Rheumatoid arthritis was diagnosed in 6 of the patients

How serious is polymyositis?

Polymyositis rarely causes death, but is associated with lung, and heart disease, as well as an increased risk of certain cancers, such as bladder cancer and lymphoma. Onset of polymyositis is gradual over several months. Initially, patients may experience fevers, weight loss and a general feeling of unwellness.

What are the differential diagnoses for polymyositis?

Symmetrical muscle weakness in the shoulders/upper arms or hips/upper legs and trunk

  • Elevation of serum levels of skeletal muscle-associated enzymes: CK,aldolase,lactate dehydrogenase (LD or LDH),transaminases (ALT/SGPT and AST/SGOT)
  • Muscle pain on grasping or spontaneous pain