What are the side effects of Trimebutine?

What are the side effects of Trimebutine?

SIDE EFFECTS: Dry mouth, foul taste, nausea, diarrhea, constipation, drowsiness, dizziness, fatigue or headache may occur. If any of these effects continue or become bothersome, inform your doctor. To avoid dizziness when rising from a seated or lying position, get up slowly.

What is Trimebutine used to treat?

It is used to treat symptoms (e.g., abdominal pain/fullness, gas, diarrhea, constipation) of irritable bowel syndrome (spastic colon). Trimebutine is also used to restart the movement of the gut after abdominal surgery and to prevent intestinal blockage (paralytic ileus).

How long does it take for Trimebutine to work?

The free base form or salt form of trimebutine are rapidly absorbed after oral administration, with the peak plasma concentration reached after 1 hour of ingestion 3. The time to reach peak plasma concentration following a single oral dose of 200mg trimebutine is 0.80 hours 8.

Is Trimebutine an antibiotic?

Trimebutine is a mentioned “non-antibiotic” and the exact mechanism leading to its in vitro bacteriostatic/bactericidal effect observed in our study is not clear. Therefore, further research is needed to investigate any potential effect of trimebutine in bacterial growth and/or metabolism.

When is the best time to take Trimebutine?

Take this medication by mouth before meals, usually 3 times daily or as directed by your doctor. Dosage is based on your medical condition and response to treatment. Do not increase the dose, take this medication more often, or continue taking it for longer than prescribed.

Is Trimebutine a narcotic?

Peripheral narcotic opiate antagonists (trimebutine and fedotozine), serotonin antagonists (tegaserod), and muscarinic antagonists (zamifenacin) are being studied.

Does Trimebutine cause constipation?

Dry mouth, heartburn, nausea, diarrhea, constipation, drowsiness, dizziness, tiredness or headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.


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