What does VZV IgG positive mean?
What does VZV IgG positive mean?
A positive IgG result indicates the presence of antibodies to varicella zoster virus. – The test cannot distinguish between past infection and current infection though, so a positive result could indicate active infection and not immunity.
How do you interpret the antibody results for varicella zoster?
Interpretation
- A positive IgG result coupled with a positive IgM result suggests recent infection with varicella-zoster virus (VZV).
- A positive IgG result coupled with a negative IgM result indicates previous vaccination to or infection with VZV.
What is the varicella-zoster antibody?
Varicella-Zoster Virus Antibody (IgG) – Varicella-Zoster Virus (VZV) causes chicken pox and when reactivated, potentially decades later, causes shingles. Twenty percent of adults will develop shingles, a rash or blister of the skin that may cause severe pain.
What is varicella-zoster IgG antibody?
If testing is done to see if you are at risk of developing an infection and it finds varicella-related immunoglobulin G (IgG) antibodies in your blood, it means you are immune. You have had a chickenpox infection or have been immunized successfully.
What is VZV antibody?
This test looks for antibodies in your blood that your body makes against the varicella-zoster virus. The varicella-zoster virus is very contagious. It can cause two health problems: chickenpox and shingles.
What is varicella-zoster IgG normal range?
165.0 IV or greater: Positive – IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection. 0.90 ISR or less: Negative – No significant level of detectable varicella-zoster virus IgM antibody. 0.91-1.09 ISR: Equivocal – Repeat testing in 10-14 days may be helpful.
How do you read varicella test results?
0.8 AI or less: Negative – No significant level of detectable varicella- zoster IgG antibody. 0.9-1.0 AI: Equivocal – Repeat testing in 10-14 days may be helpful. 1.1 AI or greater: Positive – IgG antibody to varicella-zoster detected, which may indicate a current or past exposure/immunization to varicella-zoster.
What kind of virus is VZV?
Varicella-Zoster Virus (VZV) VZV is a DNA virus and is a member of the herpesvirus group. Like other herpesviruses, VZV persists in the body as a latent infection after the primary (first) infection; VZV persists in sensory nerve ganglia. Primary infection with VZV results in varicella.
Which infection is caused by varicella zoster virus?
Varicella (chickenpox) is an acute infectious disease. It is caused by varicella-zoster virus (VZV), which is a DNA virus that is a member of the herpesvirus group. After the primary infection, VZV stays in the body (in the sensory nerve ganglia) as a latent infection. Primary infection with VZV causes varicella.
How long do varicella antibodies last after infection?
After VZV infection, IgG and IgM antibodies appear 2 to 5 days after the rash and show the highest titers at 2 to 3 weeks. The VZV IgM antibody levels then rapidly decrease and cannot be detected at 1 year after infection, and the IgG antibody levels gradually decrease, showing positive test results for several years.