What is Corynebacterium Kutscheri?
What is Corynebacterium Kutscheri?
Corynebacterium kutscheri is a common bacterium isolated from the oral cavity of healthy mice and rats. We report the first well-documented case of C. kutscheri human infection which followed a rat bite. The microorganism was identified by conventional biochemical tests and confirmed by 16S rRNA gene sequence analysis.
Where is Corynebacterium Kutscheri found?
Corynebacterium kutscheri is a gram-positive coryneform (club-shaped) bacterium which can be found in soil, sewage, and marine environments, and has been explored for possible utility of bioremediation of oil spills (Oyetibo et al., 2013). In rats, mice, guinea pigs, and hamsters, C.
Is Corynebacterium positive or negative?
Corynebacterium diphtheriae is a Gram-positive nonmotile, club-shaped bacillus. Strains growing in tissue, or older cultures in vitro, contain thin spots in their cell walls that allow decolorization during the Gram stain and result in a Gram-variable reaction.
What disease is caused by Corynebacterium?
Diphtheria is a serious infection caused by strains of bacteria called Corynebacterium diphtheriae that make toxin (poison). It can lead to difficulty breathing, heart failure, paralysis, and even death. CDC recommends vaccines for infants, children, teens, and adults to prevent diphtheria.
Where does Corynebacterium come from?
Habitat. Corynebacterium species occur commonly in nature in soil, water, plants, and food products. The nondiphtheiroid Corynebacterium species can even be found in the mucosa and normal skin flora of humans and animals.
How do you treat Corynebacterium?
Antibiotics are the treatment of choice for nondiphtherial corynebacteria infections. Many species and groups are sensitive to various antibiotics, including penicillins, macrolide antibiotics, rifampin, and fluoroquinolones. However, antibiotic susceptibility can vary, and susceptibility testing is recommended.
How common is Corynebacterium?
They are ubiquitous and can be found on the skin and in the upper respiratory and gastrointestinal tracts. The primary pathogen in this group is Corynebacterium diphtheriae, the etiologic agent of diphtheria. Additional corynebacteria include 45 species, 30 of which on rare occasion cause human disease.
How do you test for Corynebacterium?
Basic tests for Corynebacteria identification include Gram staining and cell morphology, size, pigmentation, odour and haemolysis of colonies, CAMP reaction, lipophilia, motility and biochemical tests such as catalase and pyrazinamidase production, nitrate reduction, urea hydrolysis, esculin hydrolysis, acid production …
What part of the human body does Corynebacterium colonize?
Most commonly affected areas include heart, muscle, peripheral nerves, adrenal glands, kidneys, liver, and spleen (rather comprehensive). The diphtheria toxin works by causing the death of eukaryotic cells and tissues by inhibiting protein synthesis in the cells. Two key factors aid C.