What is small cell bone cancer?

What is small cell bone cancer?

Background: Small cell osteosarcoma of bone is a rare form of osteosarcoma, with an incidence rate of 1.3%. This tumor must be differentiated from other small cell malignancies because of treatment considerations, particularly patient response to chemotherapy.

Are there different types of osteosarcoma?

There are 2 types of osteosarcoma. Each type of osteosarcoma has different subtypes. The type and subtype of osteosarcoma is determined by looking at the tumor cells through a microscope.

Which osteosarcoma has best prognosis?

As for tumor location, several studies have reported the consistent conclusion that osteosarcomas of the extremities have a better survival than the axial osteosarcomas [12,13].

How long does osteosarcoma take to grow?

The vast majority of osteosarcomas are so-called “random cases”, where no specific causes or predisposing risk factors can be identified. In young people, the development of the tumour appears to be in some way related to periods in life with rapid bone growth, hence the average for tumour development is 14-16 years.

Is small cell cancer worse?

Small cell cancers vary , depending on the expression of specific genes. Some types are more aggressive than others, but generally, small cell cancer is more aggressive than non-small cell lung cancer.

Is small cell cancer curable?

Extensive-stage small cell lung cancer is not considered to be a curable disease. The goals of therapy are to relieve symptoms, maintain quality of life, and prolong patient survival.

How curable is osteosarcoma?

Today, about 3 out of 4 people who have osteosarcoma can be cured if the cancer hasn’t spread to other parts of the body. Almost everyone who is treated with limb-sparing surgery ends up with that arm or leg working well. Many people who have osteosarcoma will need physical therapy for several months after surgery.

How is small round cell osteosarcoma differentiated from other primary bone cancer?

Small round cell osteosarcoma is a very rare type of osteosarcoma, histologically mimicking other small round cell malignancies of bone, most notably Ewing sarcoma. To distinguish small cell osteosarcoma from other primary small cell malignancies of bone, we evaluated the immunohistochemical (IHC) e …

What is osteosarcoma?

Osteosarcoma „Definitions:Definitions: „A mesenchymal malignancy (malignant spindle cells) A mesenchymal malignancy (malignant spindle cells) that differentiates to produce osteoid/immature that differentiates to produce osteoid/immature bonebone

What is the difference between primary and secondary osteosarcoma?

„Secondary Osteosarcoma: arises from a precursor Secondary Osteosarcoma: arises from a precursor lesion to one that is metastatic from a primary lesion to one that is metastatic from a primary osteosarcomaosteosarcoma

What is low grade intramedullary osteosarcoma?

„Microscopically, low grade intramedullary Microscopically, low grade intramedullary osteosarcoma looks similar to a parosteal osteosarcoma looks similar to a parosteal osteosarcomaosteosarcoma „Fibroblastic tumor producing bone Fibroblastic tumor producing bone (osteoid/immature bone)(osteoid/immature bone)