What is the product of chymotrypsin?

What is the product of chymotrypsin?

Chymotrypsin (EC 3.4. 21.1) is another serine protease produced by the pancreas that hydrolyzes the peptide bonds of tryptophan, leucine, tyrosine, and phenylalanine.

What is the substrate specificity of chymotrypsin?

Chymotrypsin, like most enzymes, is specific in the types of substrates with which it reacts. As a protease, it cleaves polypeptides, and its inherent specificity allows it to act only on the carboxy-terminal of aromatic residues.

What substrate does chymotrypsin decompose?

Chymotrypsin is a digestive enzyme that breaks down protein in the duodenum of the small intestine.

What is the structure of chymotrypsin?

The overall chymotrypsin molecule is folded into two domains, each containing six beta strands arranged as antiparallel sheets which form a circular structure known as a beta barrel. (rotate the molecule until you are looking down through the barrel or at right angles to the barrel).

What is the substrate of trypsin?

Trypsin from each source can differ slightly in activity, but the natural substrate for the enzyme is generally any peptide that contains Lys or Arg. The specificity of trypsin allows it to serve both digestive and regulatory functions.

Where is chymotrypsin produced?

the pancreas
Chymotrypsin is synthesized in the pancreas as the zymogen chymotrypsinogen (or pre-chymotrypsin).

What is the substrate for trypsin?

What is the substrate and product of protease?

Where enzymes are produced

Enzyme Substrate End-products
Protease Protein Amino acids
Lipase Lipids (fats and oils) Fatty acids and glycerol
Pancreatic amylase Starch Maltose
Maltase Maltose Glucose

How is the structure of chymotrypsin related to its function?

Chymotrypsin: Structure The structure of chymotrypsin selectively cleaves aromatic amino acids due to the hydrophobic pocket at the active site. This means that only sections of the protein that are hydrophobic (such as aromatic portions) will favorably go into this pocket for the reaction to occur.

How is a substrate like a lock and key?

The specific action of an enzyme with a single substrate can be explained using a Lock and Key analogy first postulated in 1894 by Emil Fischer. In this analogy, the lock is the enzyme and the key is the substrate. Only the correctly sized key (substrate) fits into the key hole (active site) of the lock (enzyme).

What is the substrate of acetylcholinesterase?

AChE substrate Acetylcholinesterase hydrolysizes the neurotransmitter acetylcholine (ACh), producing choline and an acetate group.

Recent Posts