What is the test for scrub typhus?
What is the test for scrub typhus?
The laboratory-based diagnosis of scrub typhus relies on serological assays like the Weil–Felix test, indirect Immunofluorescence assays, indirect immunoperoxidase assays, enzyme-linked immunosorbent assay (ELISA) and immunochromatographic tests (ICT), etc.
Why is scrub typhus called so?
Scrub typhus, named because of its initial occurrence in areas of scrub vegetation, was first discovered in Japan in 1899, but it was not isolated until 1930. The disease occurs in Southeast Asia, including Thailand, India, Australia, Russia, Korea, the Pacific Islands, and Japan Chang (1995), Seong et al (2001).
What is scrub typhus IgG?
The Scrub Typhus Detect™ IgG ELISA test for exposure to Orientia tsutsugamushi (OT; formerly Rickettsia) is an ELISA assay system for the detection of IgG antibodies in human serum to OT-derived recombinant antigen. For research use only. Not for use in diagnostic procedures.
What is IgM scrub typhus?
Intended Use. The Scrub Typhus Detect IgM ELISA test is an ELISA assay system for the detection of IgM antibodies in human serum to Orientia tsutsugamushi (OT; formerly Rickettsia) derived recombinant antigen (1-10). This test is to aid in the diagnosis of human exposure to OT species.
How does typhus start?
Flea-borne typhus is spread to people through contact with infected fleas. Fleas become infected when they bite infected animals, such as rats, cats, or opossums. When an infected flea bites a person or animal, the bite breaks the skin, causing a wound.
What is the treatment for scrub typhus?
Scrub typhus should be treated with the antibiotic doxycycline. Doxycycline can be used in persons of any age. Antibiotics are most effective if given soon after symptoms begin. People who are treated early with doxycycline usually recover quickly.
Is scrub typhus serious?
Scrub typhus is a life-threatening infectious disease that presents as an acute undifferentiated febrile illness.
What is scrub typhus IgM positive?
The Scrub Typhus Detect™ IgM ELISA for exposure to Orientia tsutsugamushi (OT; formerly Rickettsia) is an ELISA system for the detection of IgM antibodies in human serum to OT-derived recombinant antigen. This test is for research use only. Not for use in diagnostic procedures.
Which antibiotic is best for scrub typhus?
So far, doxycycline, azithromycin, and chloramphenicol are common antibiotics for treating scrub typhus. Chloramphenicol and tetracycline are efficacious therapies, but both are contraindicated in pregnant women and children. Increasing numbers of antibiotics have been reported to be efficacious against scrub typhus.