What is Spheronization process?

What is Spheronization process?

Spheronization is the process where extrudates (the output from an extruder) are shaped into small rounded or spherical granules. In practice these usually vary in size from 0.4 to about 3.0 mm. The use of these spheroids can be relevant for a wide variety of industries.

What is Pelletization technique?

Pelletization is a technique to obtain pellets or spherical particles having a dimensions between 0.5 – 1.5 mm. These multiparticulate systems are either compressed into tablets or filled into capsules.

What is extrusion Spheronization?

Extrusion/spheronization is a multiple step process capable of making uniformly sized spherical particles. The process is now being widely utilized in the pharmaceutical industry.

Why Spheronization enhancer is used in manufacturing of pellets?

4) Spheronizing Enhancer: Spheronization enhancers are formulation aids that improve the production of spherical pellets, mainly during spheronization and balling processes. They not only impart plasticity onto the formulation, but also impart binding properties that are essential for pellet strength and integrity.

What are extrudates?

extrudate (plural extrudates) Material that has been extruded through a die.

What is a Marumerizer?

The Marumerizer Model QJ-230T is a laboratory spheronizer that quickly produces uniform spherical pellets. The QJ-230T is used to convert extruded powder granules into spheres ranging in size from 0.5-10.0 mm diameter.

What is pelletizing in ironmaking?

Slag pelletizing is accomplished by pouring the slag stream onto a rotating drum where the slag is thrown vertically upward. From: Blast Furnace Ironmaking, 2020.

Is used in extrusion Spheronization process?

suggested that fine particle ethyl cellulose (FPEC) is a good diluent for extrusion–spheronization [34].

What is drug layering?

Drug layering involves depositing the drug on the surface of a substrate. The most common way of depositing the drug on the substrate is by using air-suspension coating. The drug first must be dispersed in a liquid carrier, either water or an organic solvent.

What are metal extrusions?

Metal extrusion is a process used to create longer objects with a fixed profile by pushing a cylindrical billet inside a closed cavity. The end product is called an extrudate and can have several desired characteristics and qualities.